Hedger, G.; Sansom, M.S.P.(2016) Lipid interaction sites on channels, transporters and receptors: Recent insights from molecular dynamics simulations BBA Biomembranes(paper, open access)
Vogeley, L.; El Arnaout, T; Bailey J; Stansfeld, P.J.; Boland, C; Caffrey, M. (2016) Structural basis of lipoprotein signal peptidase II action and inhibition by the antibiotic globomycin Science. (paper, open access)
Gu Y; Li, H; Dong, H; Wang, Z; Zeng Y; Paterson NG; Stansfeld, P.J.; Wang, W, Dong, C (2016) Structural basis of outer membrane protein insertion by the BAM complex Nature
(paper, open access)
Li, D.; Stansfeld, P.J.; Sansom, M.S.P.; et al.; Caffrey, M. (2015) Ternary structure reveals mechanism of a membrane diacylglycerol kinase. Nature Communications.
(paper, open access)
Hanson, S.M.; Sansom, M.S.P.; Becker, E.B.E. (2015)
Modeling Suggests TRPC3 Hydrogen Bonding and Not Phosphorylation Contributes to the Ataxia Phenotype of the Moonwalker Mouse.
Structure
(paper, open access)
Stansfeld, P.J.;Goose, J.E.;Caffrey, M.; Carpenter, E.P.; Parker, J.L,; Newstead, S.; Sansom, M.S.P. (2015)
MemProtMD: Automated Insertion of Membrane Protein Structures into Explicit Lipid Membranes.
Structure
(paper, open access)
Jefferys, E.; Sands, Z.A.; Shi, J.; Sansom, M.S.P.; Fowler, P.W. (2015)
Alchembed: A Computational Method for Incorporating Multiple Proteins into Complex Lipid Geometries.
JCTC
(paper, open access)
Hedger, G..; Sansom, M.S.P.; Koldsoe, H. (2015)
The juxtamembrane regions of human receptor tyrosine kinases exhibit conserved interaction sites with anionic lipids.
Nature Scientific Reports
(paper, open access)
Hanson, S.M.; Newstead, S.; Swartz, K.J., Sansom, M.S.P. (2015)
Capsaicin Interaction with TRPV1 Channels in a Lipid Bilayer: Molecular Dynamics Simulation.
Biophysical Journal
(paper, open access)
Kalli, A.C.; Sansom, M.S.P.; Reithmeier, R.A.F. (2015)
Molecular Dynamics Simulations of the Bacterial UraA H+-Uracil Symporter in Lipid Bilayers Reveal a Closed State and a Selective Interaction with Cardiolipin.
PlOS Comp. Biol.
(paper, open access)
Benoist Laurent, Chavent, M.; Cragnolini, T.; Dahl, A.C.E.; Pasquali, S.; Derreumaux, P.; Sansom, M.S.P.; Baaden, M. (2014)
Epock: rapid analysis of protein pocket dynamics.
Bioinformatics
(paper, open access)
Aryal, P.; Abd-Wahab, F.; Bucci, G; Sansom, M.S.P.; Tucker, Stephen J. (2014)
Influence of Lipids on the Hydrophobic Barrier within the Pore of the TWIK-1 K2P Channel.
Channels
(paper, open access)
Koldsoe, H.K.; Shorthouse,D.; Helie,J.; Sansom, M.S.P. (2014)
Lipid Clustering Correlates with Membrane Curvature as Revealed by Molecular Simulations of Complex Lipid Bilayers.
PLoS Comp Biol.
(paper, open access)
Trick, J.L.; Wallace, E.J.; Bayley, H.; Sansom, M.S.P. (2014)
Designing a Hydrophobic Barrier within Biomimetic Nanopores.
ACS Nano
(paper, open access)
Rouse, S.L.; Sansom, M.S.P. (2014)
Interactions of Lipids and Detergents with a Viral Ion Channel Protein: Molecular Dynamics Simulation Studies.
J. Phys. Chem. B
(paper, open access)
Chavent, M.; Chetwynd, A.P.; Stansfeld,P.J.; Sansom, M.S.P. (2014)
Dimerization of the EphA1 Receptor Tyrosine Kinase Transmembrane Domain: Insights into the Mechanism of Receptor Activation.
Biochemistry
(paper, open access)
Fowler, P.W.;Bollepalli, M.K.; Rapedius, M.; Nematian, E.; Shang, L; Sansom, M.S.P. ; Tucker, S.J; Baukrowitz, T. (2014)
Insights into the structural nature of the transition state in the Kir channel gating pathway.
Channels
(paper, open access)
Kalli, A.C.; Sansom, M.S.P. (2014)
Interactions of peripheral proteins with model membranes as viewed by molecular dynamics simulations.
Biochemical Society Transactions
(paper, open access)
Halim, K.B.; Koldso, H.K. ; Sansom, M.S.P. (2014)
Interactions of the EGFR juxtamembrane domain with PIP2-containing lipid bilayers: Insights from multiscale molecular dynamics simulations.
Biochimica et biophysica acta
(paper, open access)
Aryal, P.; Abd-Wahab F; Bucci G; Sansom, M.S.P. and Tucker, S.J. (2014)
A hydrophobic barrier deep within the inner pore of the TWIK-1 K2P potassium channel.
Nature Communications
(paper, open access)
Aryal, P.; Sansom, M.S.P. and Tucker, S.J. (2014)
Hydrophobic Gating in Ion Channels.
Journal of Molecular Biology
(paper, open access)
J. Tan,Rouse, S.L.; Li, D.; Pye, V.D; Vogeley; L.,Brinth, A.R.; El Arnaout, T.; Whitney, J.C.; Howell, P.L.; Sansom, M.S.P. and Caffrey, M. (2014)
A conformational landscape for alginate secretion across the outer membrane of Pseudomonas aeruginosa.
Biological Crystallography
(paper, open access)
Lonsdale, R.Rouse, S.L.; Sansom, M.S.P. and Mulholland, A.J. (2014)
A Multiscale Approach to Modelling Drug Metabolism by Membrane-Bound Cytochrome P450 Enzymes.
PLOS Comp. Biol.
(paper, open access)
Bollepalli, Fowler, P.W.; Rapedius, M.; Shang, L.; Sansom, M.S.P. Tucker, S.J.; and Baukrowitz, T. (2014)
State-Dependent Network Connectivity Determines Gating in a K+ Channel.
Structure
(paper, open access)
Hall,B.A.H;Abd Halim, K.;Buyan, A.; Emmanouil, B. and Sansom, M.S.P.. (2014)
A Sidekick for Membrane Simulations: Automated Ensemble Molecular Dynamics Simulations of Transmembrane Helices.
JCTC
(paper, open access)
Kalli, A.C.; Devaney, I. and Sansom, M.S.P.. (2014)
Interactions of Phosphatase and Tensin Homologue (PTEN) Proteins with Phosphatidylinositol Phosphates: Insights from Molecular Dynamics Simulations of PTEN and Voltage Sensitive Phosphatase.
Biochemistry
(paper, PubMed)
Dunton, T.A.; Goose, J.E.; Gavaghan, D.J.; Sansom, M.S.P. and Osborne, J.M.(2014)
The Free Energy Landscape of Dimerization of a Membrane Protein, NanC
PLoS Comp. Bio.
(paper, open access)
Reddy, T.; Manrique, S.; Buyan, A.; Hall, B.; Chetwynd, A. and Sansom, M.S.P.. (2014)
Primary and Secondary Dimer Interfaces of the FGFR3 Transmembrane Domain: Characterization via Multiscale Molecular Dynamics Simulations.
Biochemistry
(paper, open access)
Zubcevic, L.; Bavro, V.N.; Muniz, J.R.C.; Schmidt, M.R.; Wang, S.; De Zorzi, R.; Venien-Bryan, C.; Sansom, M.S.P.; Nichols, C.G. and Tucker, S.J.(2014)
Control of KirBac3. 1 potassium channel gating at the interface between cytoplasmic domains
JBC
(paper, open access)
Jefferys,E.; Sansom, M.S.P. and Fowler, P.W.(2014)
FD169: NRas slows the rate at which a model lipid bilayer phase separates
Faraday Discussion
(paper, open access)
Chavent, M.; Reddy, T.; Goose, J.E.; Dahl, A.C.E.; Stone, J.E.; Jobard, B.J. and Sansom, M.S.P. and Osborne, J.M.(2014)
The Free Energy Landscape of Dimerization of a Membrane Protein, NanC
Faraday Discussion
(paper, open access)
Roussel, G.; Rouse, S.L.; Sansom, M.S.P.; Michaux, C. and Perpete, E.A. (2014)
The role of 2-methyl-2, 4-pentanediol in sodium dodecyl sulfate micelle dissociation unveiled by dynamic light scattering and molecular dynamics simulations
Colloids and Surfaces B: Biointerfaces
More SBCB publications available from
|