leads to the
article on the publications page.
Molecular basis of alternating access membrane transport
by the sodium-hydantoin transporter Mhp1
an achievement that has been a goal of researchers from around the world for over 25 years....)
A hydrophobic gate in an ion channel: the closed
state of the nicotinic acetylcholine receptor
Our paper in Physical Biology 3 (2006), 147–159 has
been selected for inclusion in IoP Select.
IoP Select is a special collection of journal articles, chosen by the Institute of Physics Editors based on one or more of the following criteria: Substantial advances or significant breakthroughs, a high degree of novelty, significant impact on future research
Qualifying articles are published first in the source journal and then become free for 365 days from the date they enter the Select service.
Physical Biology also used one of our figures as a cover image for the issue.
Influence of geometry, surface character, and
flexibility on the permeation of ions and water through biological pores
Our paper in Physical Biology 1 (2004), 42-52 (free
pdf)
has been chosen as one of the highlights of the articles published
in Physical Biology in 2004 and 2005. To date (2008) this is the
most cited article in Physical Biology and earned the
2008 Physical Biology Citations Award.
Visions of Science 2005: Ion
channel in the nervous system
An image
of the water density in the M2 helices of the nicotinic acetylcholine
receptor was awarded a Highly commended in the Concepts
category of the Visions of Science 2005 competition.
Visions of Science is a photographic awards scheme organised by Novartis Pharmaceuticals and co-sponsored by the Daily Telegraph to encourage ongoing discussion about science. [...] To the judges of the Awards, a Vision of Science is an attention-grabbing image that gives new insight into the world of science and the workings of nature. It may show something never seen before, it may explain a scientific phenomenon, it may illustrate scientific data or it may simply be an image that shows the beauty of science.
This image and many other, even more fascinating ones can be seen as large prints in a touring exhibition.
The science behind the image is described in O. Beckstein and M. S. P. Sansom, A Hydrophobic Gate in an Ion Channel: The Closed State of the Nicotinic Acetylcholine Receptor.
The image was created by loading the average water density from a molecular dynamics simulation (produced by my gridcount tools) and the M2 helices of nAChR into VMD and rendering it with Raster3D 2.7c.
Liquid-vapour oscillations of water in hydrophobic
nano pores